Interurban Clinical Club

williamExcerpt from “The Interurban Clinical Club (1905-1994): A Record of Achievement in Clinical Science” by A. McGehee Harvey, M.D.; Sc.D. (Hon.) “William Osler founded the Interurban Clinical Club in 1905 for the purpose of exchanging ideas and fellowship among medical teachers in some of the leading Eastern medical schools. Since then, twice a year (with a few exceptions during World War II), one and one-half day meetings have been held in rotation first in Baltimore, New York, Boston and Philadelphia. A few years after the organization of the Club, members from New Haven were added. The five to nine active members from each city are chosen from the departments of medicine, pediatrics, neurology and psychiatry at the university medical schools of JohnsHopkins, Maryland, Pennsylvania, Temple, Jefferson, Columbia, Cornell, New York, Yale, Harvard, Tufts, Boston, Einstein, Downstate (Long Island) and from the Rockefeller Institute (later University). Many emeritus members (those members who have reached the age of 55 and those who have moved away from the five cities) join the active members in participating in the meetings.”

“Osler recognized that such a club organized for internists would be a way to advance medicine in America in a unique way…Everyone invited received a note as follows: ‘It is proposed to start among a few of the younger men in the Eastern cities an Interurban Club on lines somewhat similar to the Society of Clinical Surgery. The number of members will be limited. The objects of the Club will be: (1) to stimulate the study of internal medicine, (2) by mutual intercourse and discussion to improve our methods of work and teaching, (3) to promote the scientific investigation of disease, (4) to increase our knowledge of the methods of work in other clinics than our own. It is proposed to meet twice a year to have demonstrations and discussions but not set papers. The program of each meeting is to be supplied by the men in the city in which the meeting is being held…’”


209th Meeting of the Interurban Clinical Club
Smilow Center for Translational Research
University of Pennsylvania
3400 Civic Center Blvd., Philadelphia, PA 19104
Room 9-146
Friday, April 4, 2014

8.15 amContinental Breakfast Smilow Center Conference Lobby, Room 9-146

9.15 amWelcoming Remarks and Opening
Charles Abrams, M.D. Director, PENN-CHOP Blood Center for Patient Care & Discovery Associate Chief, Division of Hematology-Oncology University of Pennsylvania

Jonathan A. Epstein, MD William Wikoff Smith Professor of Medicine Chair, Department of Cell and Developmental Biology Scientific Director, Penn Cardiovascular Institute University of Pennsylvania

9.30 am“Stalking the wards for blood disease as a pediatric physician scientist” Mitchell J. Weiss, M.D., Ph.D., Jane Fishman Grinberg Professor of Pediatrics The Children’s Hospital of Philadelphia

10.00 am “The BRCA Tumor Suppressor Network” Roger A. Greenberg, M.D., Ph.D., Abramson Family Cancer Research Institute, University of Pennsylvania

10:30 -10:45 am Break

10:45 am “Using genetics to uncover novel antiviral targets” Sara Cherry, Ph.D., Associate Professor, Department of Microbiology, University of Pennsylvania

11:15 am“Targeting macrophages for cancer immunotherapy” Sir William Osler Young Investigator Award, Gregory L. Beatty, M.D., Ph.D., Assistant Professor, Division of Hematology-Oncology, University of Pennsylvania

12:00 12:45 pmLunch in Smilow Center for Translational Medicine Conference Room 9-100 (Members Only) “Opportunities for treatment of cancer through cancer cell-autonomous And non-autonomous mechanisms” D. Gary Gilliland, M.D., Ph.D., Vice Dean & Vice President, Precision Medicine

12:45-1:45 pmGuided Tour, University of Pennsylvania Museum of Archaeology & Anthropology, 3260 South Street, Philadelphia PA

1:45 pm“Reactivation of developmentally silenced globin genes by forced chromatin looping” Gerd A. Blobel, M.D., Ph.D., Frank E. Weise III Endowed Chair of Pediatrics, The Children’s Hospital of Philadelphia

2:15 pm“New insights into mammalian physiology from lymphatics”, Mark L. Kahn, M.D., B.A., Professor of Medicine, Penn Cardiovascular Institute, University of Pennsylvania

2:45 pm“Hematopoietic stem cell formation – lessons from the embryo” Nancy Speck, Ph.D., Professor of Cell and Developmental Biology, Cancer Biology, University of Pennsylvania

3:15 pmBreak

3:30 pm “The development and function of brown and beige adipocytes” Patrick Seale, Ph.D., Assistant Professor of Cell and Developmental Biology, University of Pennsylvania

4:00 pm“New biology and therapeutic targets inspired by human genetics” Daniel J. Rader, M.D., Chief, Division of Translational Medicine and Human Genetics, Director, Preventive Cardiovascular Medicine and Lipid Clinic, Director, Clinical and Translational Research Center, Associate Director, Institute for Translational Medicine and Therapeutics, Director, Cardiovascular Metabolism Unit, Institute for Diabetes, Obesity, & Metabolism, University of Pennsylvania

4:45 pmBusiness Meeting (Members Only)

6:00 pm Cocktail Reception and Black Tie Dinner, The Physick House, 321 S. 4th Street, Philadelphia, PA 19106

8:00 pm “Megatrends: Predictions for the Future of the American Health Care System” Ezekiel J. Emanuel, M.D., Ph.D., Vice Provost for Global Initiatives, Chair, Medical Ethics and Health Policy, University of Pennsylvania

9:00 pmConclusion