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Sir William Osler
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Excerpt from "The Interurban Clinical Club (1905-1994): A Record of Achievement in Clinical Science" by A. McGehee Harvey, M.D.; Sc.D. (Hon.)
"William Osler founded the Interurban Clinical Club in 1905 for the purpose of exchanging ideas and fellowship among medical teachers in some of the leading Eastern medical schools. Since then, twice a year (with a few exceptions during World War II), one and one-half day meetings have been held in rotation first in Baltimore, New York, Boston and Philadelphia. A few years after the organization of the Club, members from New Haven were added. The five to nine active members from each city are chosen from the departments of medicine, pediatrics, neurology and psychiatry at the university medical schools of Johns Hopkins, Maryland, Pennsylvania, Temple, Jefferson, Columbia, Cornell, New York, Yale, Harvard, Tufts, Boston, Einstein, Downstate (Long Island) and from the Rockefeller Institute (later University). Many emeritus members (those members who have reached the age of 55 and those who have moved away from the five cities) join the active members in participating in the meetings."
"Osler recognized that such a club organized for internists would be a way to advance medicine in America in a unique way...Everyone invited received a note as follows: 'It is proposed to start among a few of the younger men in the Eastern cities an Interurban Club on lines somewhat similar to the Society of Clinical Surgery. The number of members will be limited. The objects of the Club will be: (1) to stimulate the study of internal medicine, (2) by mutual intercourse and discussion to improve our methods of work and teaching, (3) to promote the scientific investigation of disease, (4) to increase our knowledge of the methods of work in other clinics than our own. It is proposed to meet twice a year to have demonstrations and discussions but not set papers. The program of each meeting is to be supplied by the men in the city in which the meeting is being held...'"
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- FOUNDER - Sir William Osler
- DECEASED - Drs. JD Steele(1908); EG Janeway(1911); AOJ Kelly(1911); RH Fitz(1913); SW Mitchell(1914); TC Janeway(1917); W Osler(1919); J Howland(1926); WB James(1927); TW Salmon(1927); FS Meara(1927); J Sailer(1928); EH Funk(1932); WS Thayer(1932); NB Foster(1933); T McCrae(1935); J Wyckoff(1937); HRM Landis(1937); TB Futcher(1938); TR Boggs(1938); A Stengel(1939); RC Cobot(1939); WP Soper(1939); CP Emerson(1939); D Reisman(1940); CNB Camac(1940); AK Krause(1941); FT Lord(1941); KD Blackfan(1941); SW Lambert(1942); JD Trask(1942); HR Geyelin(1942); L Barker(1943); WO Abbott(1943); DL Edsall(1945); L Hamman(1946); CL Hoagland(1946); A Winkler(1947); R West(1949); SR Miller(1949); GR Minot(1950); LA Conner(1951); HA Christian(1951); FG Blake(1952); GM Mackenzie(1952); OM Schloss(1952); WT Longcope(1953); FF Schwentker(1954); EP Carter(1955); JL Lilienthal, Jr(1955); JP Peters(1955); JH Pratt(1956); HL Amoss(1956); H Emerson (1957); EA Strecker(1959); G Draper(1959); LG Rowntree(1959); WD Stroud(1959); JL Gamble(1959); CP Rhoads(1959); HW Jones(1959); JC Turner(1961); EP Joslin(1962); TE Machella(1962); G Blumer(1962); TM Rivers(1962); L Wilkins(1963); W Bauer(1963); FB Talbot(1964); DC Darrow(1965); RL Cecil(1965); GW Norris(1965); CC Wolferth(1965); AN Richards(1966); RI Cole(1966); HM Thomas, Jr(1966); S Cobb(1968); GF Powers(1968); PL Boisvert(1968); W Tileston(1969); EA Park(1969); F Albright(1969); CNH Long(1970); WB Wood, Jr(1971); FL Horsfall, Jr(1971); EA Locke(1971); CS Keefer(1972); CM Macleod(1972); J Stokes, Jr(1972); SA Berson(1972); DW Richards(1973); RF Loeb(1973); L Welt(1973); WS Tillett(1974); LE Holt, Jr(1974); T Durant(1977); EF Gildea(1977); HL Blumgart(1977); AA Weech(1977); R Ward(1977); EC Andrus(1978); B Alexander(1978); J Bordley, III(1979); FDW Lukens(1979); JT King(1979); FJ Ingelfinger(1980); DM Pillsbury(1980); JC Fox(1980); CA Janeway(1981); W McDermott(1981); TG Miller(1981); RH Green(1981); FB Bang(1981); AM Fisher(1982); GS Mirick(1983); HG Kunkel(1984); JT Wearn(1984); JE Howard(1985); G Klatskin(1986); R Ney(1986); AM Bongiovanni(1986); AM Butler(1986); EM Landis(1987); TS Danowski(1987); AVN Goodyear(1988); SH Ingbar(1988); I Starr(1989); EH Luckey(1989); WB Castle(1990); IL Bennett, Jr(1990); FC Wood(1991); D Goodman(1991); S Sherry(1993); S Wolff(1994); L Thomas(1994); DE Rogers(1994); N Talbot(1994); JA Shannon(1995); TB Conner(1995); L Dexter(1995); RH Ebert(1996); GH Mudge(1996); TW Smith(1997); J Haddad(1997); EC Cumen(1997); A McGehee Harvey(1998); SE Bradley(1999); SP Asper(1999); SS Kety; C Key(2000); C McEwan(2000); A Feinstein(2001); R Berliner(2002); JM Eisenberg(2002); GA Perera(2002); JR Elkinton; RM Donaldson(2003); C Janeway(2003); A Erslev(2003); N Levinsky(2004); HS Lawrence(2004); H Eder(2004); L Eichna(2002); WG Walker(2004); GW Thorn(2004); F Rosen(2005); M McCarty(2005); SJ Farber(2006); R Austrian(2007); SS Shapiro(2007); S Segal(2007); EH Sonnenblick(2007); R Adams(2008); RD Utiger(2008); VA McKusick(2008); FH Epstein(2008); WB Schwartz(2009)
- EMERITUS AND HONORARY - Drs. P Zamecnik; JB Wyngaarden; FP Chinard; WJ Williams; CL Conley; PK Bondy; RE Cooke; AP Fishman; IM London; TG Schnable, Jr; QB Deming; IH Scheinberg; E Atkins; TR Hendrix; A Leaf; PJ Mulrow; NS Bricker; H Hiatt; SC Finch; NP Christy; AG Bearn; S Reiman; RB Hornick; M Goldberg; RS Ross; HM Spiro; M Walser; RP Cox; BS Blumberg; JE Wood; KL Isselbacher; S Reichlin; JH Jandl; H Williams; A Bollet; RJ Johns; AH Owens, Jr; CI Christian; A Kappas; PA Marks; A Cohen; GF Cahill;, Jr; S Krane; S Segal; DB Martin; S Greisman; KF Austen; J Hirsch; P Felig; E Braunwald; N Spritz; H Weiss; J Bertino; G Weissman; R Rifkind; SO Thier; J Scheuer; W Hazzard; VT Andriole; R Johnson; LE Rosenberg; J Martin; B Brenner; FS Kantor; G McKhann; J Potts; D Deykin; JG Bartlett; PJ Cannon; R Hirschhorn; S Karpatkin; HY Reynolds; LS Cohen; SE Malawista; OE Owen; L Lichtenstein; RG Douglas, Jr; I Surks; G Boden; JP Hayslett; R Zurier; L Landsberg; WC Maddrey; J Avruch; PN Walsh; JF Wilber; RL Nagel; JN Loeb; D Zakim; JL Boyer; TP Stossel; TP Duffy; L Sherwood; B Weksler; RW Colman; F Bunn; J Roth; D Fearon; M Weksler; G Burrow; M Weisfeldt; G Lazarus; J Forrest, Jr; A Bove; B Forget; S Cohen; SD Douglas; R Glickman; MC Carey; PW Askenase; Q Al-Awqati; WN Kelley; L Goldman; D Griffin; T Strom; B Zaret; H Samuels; D Shafritz; S Shattil; J Stobo; A Schreiber; E Holmes; A Broadus; B Diamond; CF Nathan; W Parks; JL Swain; J Griffin; JT Sylvester; RS Sherwin; AF Stewart; DL Kasper; ED Kieff; SG Kelsen; EG Neilson; M Donowitz; AC Steere; L Chess; MC Gershengorn; RI Horwitz; MM Levine; WF Crowley; P Whelton; LJ Rubin; WW Chin; HM Kronenberg; S Williams; RA Eisenberg; HM Friedman; RL Edelson; EC Cadman; DA Ausiello; VJ Dzau; AJ Marcus; J Kessler; E Benz, Jr; SB Calderwood; J Drazen; S Liebhaber; M Rosenblatt; TF Davies; F Suchy; JS Flier; FS Gorelick, K Joiner; AW Wolkoff; NE Cooke; MI Greene; MK Hostetter; H Rubin; MJ Blaser; G Brodeur; A Feldman; A Gewirtz; CW Balke; L Fried; T Shapiro; K Insogna; M Artman; S MacDonald; B Kahn; J Hoxie; J Loscalzo; J Craft; JA Elias; BN Cronstein; K High; M Barry; AP Feinberg; B Neel; P Noble; E Marban; AK Rao; NC Andrews; KA Hajjar; C Tacket; BL Hempstead; DT Scadden; GI Shulman; S Waldman; JR Bender; MJ Birnbaum; SG Emerson; J Lieberman; BJ Goldstein; RN Kitsis
- BALTIMORE - Drs. Bruce Bochner, Frederick Brancati, Hyam Levitsky, Stephen B. Liggett, Charles J. Lowenstein, Neil R. Powe, Antony Rosen, Cynthia L. Sears, Gordon F. Tomaselli, Alessio Fasano
- BOSTON - Drs. Seth L. Alper, Nancy Berliner, Richard Blumberg, Glenn Dranoff, Elizabeth Henske, Andrew Luster, Arlene Sharpe, Megan Sykes, Margaret Schipp, Ralph Weissleder, Mark Zeidel, Leonard Zon
- NEW HAVEN - Drs. Linda K. Bockenstedt, Richard Bucala, Lloyd Cantley, Judy Cho, Erol Fikrig, Thomas Gill, Michael H. Nathanson, Scott A. Rivkees, John J. Wysolmerski, Lawrence Young
- NEW YORK - Drs. Craig T. Basson, Edward Fisher, Paul Frenette, Gerard Karsenty, Donald W. Landry, Andrew R. Marks, Mark Philips, Charles L. Sawyers, David Scheinberg, Edward Y. Skolnik, Jil Tardiff, Mone Zaidi
- PHILADELPHIA - Drs. Charles Abrams, Jean Bennett, Lewis Chodosh, George Cotsarelis, Adam Dicker, Wafik S. El-Deiry, Jonathan Epstein, Gary A. Koretzky, Michael Lisanti, John Maris, Michael S. Parmacek, Richard G. Pestell, Richard P. Shannon, Doris Stoffers
- COUNCILORS - Drs. Richard P. Shannon, President; Wafik S. El-Deiry, Secretary/Treasurer, Antony Rosen, Councilor, Baltimore; Megan Sykes, Councilor, Boston, John J. Wysolmerski, Councilor, New Haven; Craig T. Basson, Councilor, New York; Wafik S. El-Deiry, Councilor, Philadelphia
- PROCEDURE FOR NOMINATION OF NEW MEMBERS - Candidates for Interurban Clinical Club membership are nominated by Active Members. The nominating member constructs a letter to the INTERURBAN CLINICAL CLUB COUNCIL of approximately 2 pages summarizing professional and personal qualifications of the nominee. Typically such a letter will review the academic and scholarly achievements and scientific contributions of the individual and will provide an assessment of his/her stature in the field. Unique aspects of candidacy should be emphasized. The letter must be signed by four members (three plus nominating members). The updated CV of the nominee should be submitted with the letter. Additional letters of support may be solicited, although these are not required for the nomination. They may, however, be helpful to the Council. The original plus seven copies of the above-mentioned materials should be submitted to the Councilor of the city of the nominee. The Councilor will bring these to the Council meeting. One copy should be sent to the Secretary/Treasurer's office. For consideration at April meetings a nominee must be nominated by March 27 preceding the meeting, and for November meetings a nominee must be nominated by October 22 preceding the meeting. The nominator must fully explain the workings of the Club to the nominee and what the obligations that membership entails.
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AGENDA FOR 199th Meeting of the Interurban Clinical Club - Sir William Osler, Founder, 1905
ADVANCES IN MEDICAL RESEARCH
THE COLLEGE OF PHYSICIANS OF PHILADELPHIA
THOMSON HALL, 19 SOUTH 22nd STREET
PHILADELPHIA, PA 19103 (215) 563-3103
FRIDAY, APRIL 3, 2009
INTERURBAN CLINICAL CLUB MEETING AGENDA
8:00 a.m. Continental Breakfast – The College of Physicians of Philadelphia (Thomson Hall)
8:20 a.m. Opening of Meeting and Welcoming Remarks
The College of Physicians of Philadelphia; Thomson Hall
Wafik S. El-Deiry, M.D., Ph.D., Philadelphia ICC Councilor, American Cancer Society Research Professor, Professor of Medicine, Genetics, and Pharmacology, Co-Director, Radiation Biology and Imaging Program, Abramson Cancer Center, University of Pennsylvania School of Medicine
8:30 a.m. “Wnt Signaling, Chromatin Structure, and Poised Transcription in Early Development” Peter S. Klein, M.D., Ph.D., Associate Professor, Departments of Medicine, and Cell and Developmental Biology, University of Pennsylvania School of Medicine
9:00 a.m. “Sleepless flies: Probing the genetics of sleep” Amita Seghal, Ph.D., Professor of Neuroscience, Investigator, Howard Hughes Medical Institute, University of Pennsylvania School of Medicine
9:30 a.m. “Stem Cells and Immunity in the 21st Century - The Quest for Vaccines against Stealthy Pathogens” Steven L. Reiner, M.D., Professor, Department of Medicine, Division of Infectious Diseases and Abramson Family Cancer Research Institute, Chair, Immunology Graduate Group, University of Pennsylvania School of Medicine
10:00 a.m. "Challenges in Spanning the Biology-Medicine Chasm-Lessons from Ovarian Cancer" Michael V. Seiden, M.D., Ph.D., President and CEO, Fox Chase Cancer Center
10:30 a.m. Coffee Break
11:00 “Developmental Biology Rounds: Molecular control of pancreatic development and cancer” Ben stanger, M.D., Ph.D., Assistant Professor of Medicine, Division of Gastroenterology, Assistant Investigator, Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine
11:30 a.m. Sir William Osler Young Investigator Award
“Soluble and mechanical factors in liver fibrosis” Rebecca Wells, M.D., Assistant Professor, Departments of Medicine (Gastroenterology) and Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine
12:15 p.m. Luncheon Speaker: “Lessons Learned from the OTCD Trial” James M. Wilson, M.D., Ph.D., John Herr Musser Professor of Research Medicine, Professor, Department of Pathology and Laboratory Medicine, Head, Gene Therapy Program, University of Pennsylvania School of Medicine
1:15 p.m. Tour of The College of Physicians of Philadelphia Mütter Museum
2:00 p.m. “The imaging phenotype as a tool for disease characterization” Mitchell Schnall, M.D., Ph.D., Matthew J. Wilson Professor of Radiology and Vice Chair for Research, Department of Radiology, University of Pennsylvania School of Medicine
2:30 p.m. “An Aye for Gene Therapy: Preliminary Results from a Phase 1 Clinical Trial for Congenital Blindness” Jean Bennett, M.D., Ph.D., F.M. Kirby Professor, Ophthalmology, Cell and Developmental Biology, Vice Chair for Research in Ophthalmology, Senior Investigator, F.M. Kirby Center for Molecular Ophthalmology, University of Pennsylvania School of Medicine
3:00 p.m. "Caveolins in Breast Cancer Pathogenesis and Prevention: Role of the Tumor Micro-Environment" Michael P. Lisanti, M.D., Ph.D., Director, Stem Cell Biology and Regenerative Medicine Center, Director, Basic and Translational Science, Department of Medical Oncology, Landenberger Endowed Professor in Breast Cancer Research, Professor of Cancer Biology, Medical Oncology, and Biochemistry, Kimmel Cancer Center, Thomas Jefferson University
3:30 p.m. “Pediatric oncology at the crossroads: Meeting the challenge of stagnating cure rates with genomic medicine” John Maris, M.D., Chief, Division of Oncology, Associate Professor of Pediatrics, Director, Center for Childhood Cancer Research, Children’s Hospital of Philadelphia
4:00 p.m. “Hair follicle stem cells and skin regeneration” George Cotsarelis, M.D., Albert M. Kligman Associate Professor of Dermatology, Director, Program on Epithelial Regeneration and Stem Cells, University of Pennsylvania Institute for Regenerative Medicine, Director, University of Pennsylvania Hair and Scalp Clinic, University of Pennsylvania School of Medicine and Hospital of the University of Pennsylvania
4:30 p.m. Business Meeting
The College of Physicians of Philadelphia
19 S. 22nd Street
Philadelphia, PA 19103
6:30 p.m. Cocktail Reception
Union League
140 S. Broad Street
Philadelphia, PA 19102 (215) 405-9578
7:00 p.m. Dinner (Black Tie)
Union league
140 S. Broad Street
Philadelphia, PA 19102 (215) 405-9578
8:00 p.m. After Dinner Speaker
“Progress & Promise in the Fight Against Cancer”
Margaret Foti, Ph.D., M.D. (h.c.), Chief Executive Officer, American Assoc. for Cancer Research
9:00 p.m. Conclusion
Web Site:
Wafik S. El-Deiry, ICC Secretary/Treasurer
webmaster, 2005-
Email: wafik@mail.med.upenn.edu
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