Interurban Clinical Club Founder - Sir William Osler 1905
	Sir William Osler Excerpt from "The Interurban Clinical Club (1905-1994): A Record of Achievement in Clinical Science" by A. McGehee Harvey, M.D.; Sc.D. (Hon.) "William Osler founded the Interurban Clinical Club in 1905 for the purpose of exchanging ideas and fellowship among medical teachers in some of the leading Eastern medical schools. Since then, twice a year (with a few exceptions during World War II), one and one-half day meetings have been held in rotation first in Baltimore, New York, Boston and Philadelphia. A few years after the organization of the Club, members from New Haven were added. The five to nine active members from each city are chosen from the departments of medicine, pediatrics, neurology and psychiatry at the university medical schools of Johns Hopkins, Maryland, Pennsylvania, Temple, Jefferson, Columbia, Cornell, New York, Yale, Harvard, Tufts, Boston, Einstein, Downstate (Long Island) and from the Rockefeller Institute (later University). Many emeritus members (those members who have reached the age of 55 and those who have moved away from the five cities) join the active members in participating in the meetings." "Osler recognized that such a club organized for internists would be a way to advance medicine in America in a unique way...Everyone invited received a note as follows: 'It is proposed to start among a few of the younger men in the Eastern cities an Interurban Club on lines somewhat similar to the Society of Clinical Surgery. The number of members will be limited. The objects of the Club will be: (1) to stimulate the study of internal medicine, (2) by mutual intercourse and discussion to improve our methods of work and teaching, (3) to promote the scientific investigation of disease, (4) to increase our knowledge of the methods of work in other clinics than our own. It is proposed to meet twice a year to have demonstrations and discussions but not set papers. The program of each meeting is to be supplied by the men in the city in which the meeting is being held...'" FOUNDER - Sir William Osler DECEASED - Drs. JD Steele(1908); EG Janeway(1911); AOJ Kelly(1911); RH Fitz(1913); SW Mitchell(1914); TC Janeway (1917); W Osler (1919); J Howland (1926); WB James(1927); TW Salmon(1927); FS Meara(1927); J Sailer(1928); EH Funk(1932); WS Thayer(1932); NB Foster(1933); T McCrae (1935); J Wyckoff(1937); HRM Landis(1937); TB Futcher(1938); TR Boggs (1938); A Stengel(1939); R C Cobot(1939); WP Soper(1939); CP Emerson (1939); D Reisman (1940); CNB Camac(1940); AK Krause(1941); FT Lord(1941); KD Blackfan(1941); SW Lambert (1942); JD Trask (1942); HR Geyelin(1942); L Barker(1943); WO Abbott(1943); DL Edsall(1945); L Hamman(1946); CL Hoagland (1946); A Winkler(1947); R West(1949); SR Miller(1949); GR Minot(1950); LA Conner(1951); HA Christian(1951); FG Blake(1952); GM Mackenzie(1952) OM Schloss (1952); WT Longcope(1953); FF Schwentker(1954); EP Carter(1955); JL Lilienthal, Jr.(1955); JP Peters(1955); JH Pratt(1956); HL Amos (1956); H Emerson(1957); EA Strecker(1959); G Draper(1959); LG Rowntree(1959); WD Stroud(1959) JL Gamble(1959); CP Rhoades (1959) HW Jones(1959); JCTurner(1961); EP Joslin(1962); TE Machella(1962); G Blumer(1962); TM Rivers(1962); L Wilkins(1963); W Bauer(1963); FB Talbot(1964); DC Darrow(1965): RL Cecil(1965); GW Norris(1965); CC Wolferth(1965); AN Richards(1966); RI Cole(1966); HM Thomas, Jr.(1966); S Cobb(1968); GF Powers(1968); PL Boisvert (1968); W Tileston(1969); EA Park(1969); F Albright(1969); CNH Long(1970); WB Wood, Jr.(1971); FL Horsfall, Jr.((1971); EA Locke(1971); CS Keefer(1972); CM Macleod(1972); J Stokes, Jr.(1972); SA Berson(1972); DW Richards(1973); RFLoeb(1973); Welt(1973); WS Tillett(1974); LE Holt, Jr.(1974); T Durant (1977); EF Gildea(1977); HL Blumgart(1977); AA Weech(1977); R Ward (1977); EC Andrus(1978); B Alexander(1978); J Bordley(1979); FDW Lukens(1979); JT King(1979); FJ Inelfinger(1980); DM Pillsbury (1980); JC Fox(1980); CA Janeway(1981); W McDermott(1981); TG Miller(1981); RH Green(1981); FB Bang(1981); AM Fisher(1982); GS Mirick(1983); HG Kunkel(1984); JT Wearn(1984); JE Howard(1985); G. Klatskin(1986); R Ney(1986); AM Bongiovanni(1986); AM Butler(1986); EM Landis(1987); TS Danowski (1987); AVN Goodyear(1988); SH Ingbar( 1988); I Starr(1989); EH Luckey(1989); WB Castle(1990); IL Bennett, Jr.(1990); FC Woods(1991); D Goodman(1991); S Sherry(1993); S Wolff(1994); L Thomas(1994); DE Rogers(1994); N Talbot(1994); JA Shannon(1995); TB Connor(1995); L Dexter(1995); RH Ebert(1996); GH Mudge(1996); TW Smith(1997); J Haddad(1997); EC Cumen(1997); A McGehee Harvey(1998); SP Asper(1998); SE Bradley(1999); SS Kety; C Kay (2000); C McEwan(2000); A Feinstein(2001); R Berliner(2002); LW Eichna (2002); GA Perera(2002); JR Elkinton (2002); RM Donaldson(2003); C Janeway(2003); A Erslev ((2003); N Levinksy(2004); GW Thorn(2004); WG Walker (2004) HS Lawrence (2004); H Eder (2004); F Rosen (2005); M McCarty(2005) TE Woodward (2005); E Atkins (2005); SJ Farber (2006); JH Jandl (2006); R. Austrian (2007), SS Shapiro (2007); S Segal (2007); EH Sonnenblick (2007); VA McKusick (2008); RD Adams (2008); RD Utiger (2008); FH Epstein (2008); WB Schwartz (2009); TG Schnable, Jr. (2009); AG Bearn (2009); S. Karpatkin (2009); AP Fishman (2010); OE Owen (2010); A Gewirtz (2011) EMERITUS AND HONORARY - Drs. P Zamecnik; JB Wyngaarden; FP Chinard; WJ Williams; CL Conley; PK Bondy; RE Cooke; IM London; QB Deming; IH Scheinberg; TR Hendrix; A Leaf; PJ Mulrow; NS Bricker; H Hiatt; SC Finch; NP Christy; AS Relman; RB Hornick; M Goldberg; RS Ross; HM Spiro; M Walser; RP Cox; BS Blumberg; JE Wood; KL Isselbacher; S Reichlin; H Williams; A Bollett; RJ Johns; AH Owens, Jr.; CL Christian; A Kappas; PA Marks; A Cohen; GF Cahill, Jr.; S Krane; DB Martin; S Greisman; KF Austen; J Hirsch; P Felig; E Braunwald; N Spritz; H Weiss; J Bertino; G Weissman; R Rifkind; SO Thier; J Scheuer; W Hazzard; VT Andriole; R Johnson; LE Rosenberg; J Martin; B Brenner; FS Kantor; G McKhann; J Potts; D Deykin; JG Bartlett; PJ Cannon; R Hirschhorn; HY Reynolds; LS Cohen; SE Malawista; L Lichtenstein; RG Douglas, Jr.; I Surks; G Boden; JP Hayslett; R Zurier; L Landsberg; WC Maddrey; J Avruch; PN Walsh; JF Wilber; RL Nagel; JN Loeb; D Zakim; JL Boyer; TP Stossel; TP Duffy; L Sherwood; B Weksler; RW Colman; JM Eisenberg; F Bunn; J Roth; D Fearon; M Weksler; G Burrow; M Weisfeldt; G Lazarus; J Forrest, Jr.; A Bove; B Forget; S Cohen; SD Douglas; R Glickman; MC Carey; PW Askenase; Q Al-Awqati; WN Kelley; L Goldman; D Griffin; T Strom; B Zaret; H Samuels; D Shafritz; S Shattil; J Stobo A Schreiber; E Holmes; A Broadus; B Diamond; CF Nathan; W Parks; JL Swain; J Griffin; JT Sylvester; RS Sherwin; AF Stewart;; DL Kasper; ED Kieff; SG Kelsen; EG Neilson; M Donowitz; AC Steere; L Chess; MC Gershengorn; RI Horowitz; MM Levine; WF Crowley; P Whelton; LJ Rubin; WW Chin; HM Kronenberg; S Williams; RA Eisenberg; HM Friedman; RL Edelson; EC Cadman; DA Ausiello; VJ Dzau; AJ Marcus; J Kessler; E Benz, Jr.; SB Calderwood; J Drazen; S Liebhaber; M Rosenblatt; TF Davies; F Suchy; JS Flier; FS Gorelick; K Joiner; AW Wolkoff; NE Cooke; MI Greene; MK Hostetter; H Rubin; MJ Blaser; G Brodeur; A Feldman; M Levine; CW Balke; L Fried; T Shapiro; K Insogna; M Artman; S MacDonald; B Kahn; J Hoxie; J Loscalzo; J Craft; JA Elias; BN Cronstein; K High; M Barry; AP Feinberg; B Neel; P Noble; S Shapiro; E Marban; AK Rao; NC Andrews; KA Hajjar; C Tacket; BL Hempstead; DT Scadden; GI Shulman; S Waldman; JR Bender; MJ Birnbaum; SG Emerson; J Lieberman; BJ Goldstein; F Brancati; RN Kitsis; DW Landry; AR Marks; CL Sears; RE Pyeritz; MK Crow; MH Nathanson: GF Tomaselli; E Fisher; SB Liggett; CT Basson BALTIMORE - Drs. Bruce Bochner, Alessio Fasano, Hyam Levitsky, Charles J. Lowenstein, Neil R. Powe, Antony Rosen, and David L. Thomas BOSTON - Drs. Seth L. Alper, Richard Blumberg, Lynda Chin, Glenn Dranoff, Elizabeth Carson Engle, Elizabeth Henske, Andrew Luster, Arlene Sharpe, Margaret Shipp, Laurence Turka, Ralph Weissleder, Mark Zeidel, Jing Zhou and Leonard Zon NEW HAVEN - Drs. Linda K. Bockenstedt, Richard Bucala, Lloyd Cantley, Judy Cho, Marie Egan, Erol Fikrig, Thomas Gill, Kevan Herold, Thomas Lynch, Scott A. Rivkees, Michael Simons, John J. Wysolmerski and Lawrence Young NEW YORK - Drs. Andrew J. Dannenberg, Paul S. Frenette, Gerard Karsenty, Mark Phillips, Charles L. Sawyers, David Scheinberg, Edward Y. Skolnik, Megan Sykes, Jil Tardiff and Mone Zaidi PHILADELPHIA - Drs. Charles Abrams, Jean Bennett , Lewis Chodosh, George Cotsarelis , Adam Dicker, Wafik S. El-Deiry, Jonathan Epstein, Gary A. Koretzky, Michael Lisanti, John Maris, Michael S. Parmacek, Richard G. Pestell, Richard P. Shannon and Doris Stoffers COUNCILORS - Drs. John J. Wysolmerski, President; Wafik S. El-Deiry, Secretary/Treasurer, Antony Rosen, Councilor, Baltimore; Mark Zeidel, Councilor, Boston, Michael Simons, Councilor, New Haven; Mone Zaidi, Councilor, New York; Richard G. Pestell, Councilor, Philadelphia PROCEDURE FOR NOMINATION OF NEW MEMBERS - Candidates for Interurban Clinical Club membership are nominated by Active Members. The nominating member constructs a letter to the INTERURBAN CLINICAL CLUB COUNCIL of approximately 2 pages summarizing professional and personal qualifications of the nominee. Typically such a letter will review the academic and scholarly achievements and scientific contributions of the individual and will provide an assessment of his/her stature in the field. Unique aspects of candidacy should be emphasized. The letter must be signed by four members (three plus nominating members). The updated CV of the nominee should be submitted with the letter. Additional letters of support may be solicited, although these are not required for the nomination. They may, however, be helpful to the Council. The original plus seven copies of the above-mentioned materials should be submitted to the Councilor of the city of the nominee. The Councilor will bring these to the Council meeting. One copy should be sent to the Secretary/Treasurer's office. For consideration at April meetings a nominee must be nominated by March 27 preceding the meeting, and for November meetings a nominee must be nominated by October 22 preceding the meeting. The nominator must fully explain the workings of the Club to the nominee and what the obligations that membership entails. ❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊ Agenda for 203rd MEETING OF THE INTERURBAN CLINICAL CLUB ADVANCES IN MEDICAL RESEARCH: A CELEBRATION OF OSLER Mount Sinai School of Medicine Atran 4th Floor Conference Room One Gustave L. Levy Place New York, NY 10029-6574 Friday, April 1, 2011 203rd Meeting of the Interurban Clinical Club (1905-2011) “ADVANCES IN TRANSLATIONAL MEDICINE” The New York Landscape ❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊ 8:00 a.m. Welcome/Continental Breakfast Mone Zaidi, MD, PhD, New York ICC Councilor, Professor of Medicine, and Director, Mount Sinai Bone Program, Mount Sinai School of Medicine, New York 8:30 a.m. “Genetic Reprogramming in Regenerative Medicine” Ihor Lemischka, PhD, Henry M. Stratton Professor of Gene and Cell Medicine, and Director, Black Family Stem Cell Institute, Mount Sinai School of Medicine, New York 9:00 a.m. “The Role of Inflammation and Stem Cells in Cancer” Timothy Wang, MD, Dorothy L. and Daniel H. Silberberg Professor of Medicine, and Chief of the Division of Gastroenterology, College of Physicians and Surgeons, Columbia University, New York 9:30 a.m. “Prenatal Diagnosis and Therapy of Congenital Adrenal Hyperplasia” Maria New, MD, Professor of Pediatrics and Director, Adrenal Steroid Disorders Program, Mount Sinai School of Medicine, New York 10:00 a.m. Coffee 10:30 a.m. Sir William Osler Award “Genetics and Therapy of Myeloid Malignancies” Ross Levine, MD, Assistant Member and Geoffrey Beene Junior Chair, Memorial Sloan Kettering Cancer Center, and Assistant Professor of Medicine, Weill Cornell Medical School, New York 11:00 a.m. “Developing Vaccines that Elicit T-Cell Immunity” Ralph Steinman, MD, Henry G. Kunkel Professor and Senior Physician, Laboratory of Cellular Physiology and Immunology, Rockefeller University, New York 11:30 a.m. “Central Regulation of Metabolism” Christoph Buettner, MD, Assistant Professor of Medicine, Division of Endocrinology, Diabetes, and Bone Diseases, Mount Sinai School of Medicine, New York 12:00 p.m. Display of Mount Sinai’s Own Treasures, Archivist Barbara Niss 11th Floor, Annenberg Building, Mount Sinai School of Medicine, New York 1:00 p.m. Lunch, Board Room, 5th Floor, Annenberg Building, Mount Sinai School of Medicine, New York Luncheon Speaker “Fulfilling the Promise of Biomedical Research: Nurturing Innovation at an Academic Medical Center” Dennis S. Charney, MD, Anne and Joel Ehrenkranz Dean, Mount Sinai School of Medicine, and Executive Vice President for Academic Affairs, The Mount Sinai Medical Center 2:00 p.m. “Targeted Molecular Therapies in Lung Cancer” Goutham Narla, MD, PhD, Assistant Professor of Medicine and of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York 2:30 p.m. “Insights into the Regulation of Skeletal Mass, Microstructure, and Remodeling by Parathyroid Hormone through Disorders of Parathyroid Function” John Bilezikian, MD, Dorothy L. and Daniel H. Silberberg Professor of Medicine and Professor of Pharmacology, and Chief of the Division of Endocrinology, College of Physicians and Surgeons, Columbia University, New York 3:00 p.m. Coffee Break 3:30 p.m. “A Transition from Disease to Health - 2010-2020: Subclinical Cardiovascular and Mental Disease” Valentin Fuster, MD, PhD, The Richard Gorlin, MD/Heart Research Foundation Professor and Director, Mount Sinai Heart, Mount Sinai School of Medicine, New York 4:00 p.m. “Mammals, Dinosaurs, and Fungi: Is There a Connection?” Arturo Casadevall, MD, PhD, Leo and Julia Forchheimer Chair in Microbiology, and Immunology, and Chairman, Department of Microbiology and Immunology, Albert Einstein College of Medicine, New York ❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊ 4:30 p.m. Business Meeting 4th Floor Conference Room, Atran Building, Mount Sinai School of Medicine, New York, NY ❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊ 6:30 p.m. Cocktail Reception and Dinner (Black Tie) New York Academy of Medicine, 1216 Fifth Avenue at 103 Street, New York, NY 10029 8:00 p.m. “Confronting the Limits of Biologic and Medical Determinism” Barry Coller, MD, David Rockefeller Professor of Medicine, Head, Allen and Frances Adler Laboratory of Blood and Vascular Diseases, and Vice President for Medical Affairs, Rockefeller University, New York 9:00 p.m. Conclusion ❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊ Agenda for 202nd MEETING OF THE INTERURBAN CLINICAL CLUB ADVANCES IN MEDICAL RESEARCH: A CELEBRATION OF OSLER HARVARD MEDICAL SCHOOL BENJAMIN WATERHOUSE ROOM, GORDON HALL 25 SHATTUCK STREET BOSTON, MA 02115 Friday, November 5, 2010 202nd Meeting of the Interurban Clinical Club (1905-2010) ADVANCES IN MEDICAL RESEARCH ❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊ 8:00 a.m. Continental Breakfast- Benjamin Waterhouse Room, Gordon Hall 8:15 a.m. Opening of Meeting and Welcoming Remarks, Benjamin Waterhouse Room, Gordon Hall, Mark L Zeidel, M.D., Boston ICC Councilor, Herrman Ludwig Blumgart Professor of Medicine, Harvard Medical School: Chair, Department of Medicine, Beth Israel Deaconess Medical Center 8:30 a.m. “Control of T cell Homeostasis by the Suppressor Gene PTEN” Lawrence S. Turka, M.D., Lecturer of Medicine, Harvard Medical School: Co-Chief, Division of Transplant Immunology, Beth Israel Deaconess Medical Center 9:00 a.m. “The Noncoding Revolution” Pier Paulo Pandolfi, M.D., Ph.D., George S. Reisman Professor of Medicine, Harvard Medical School; Chair, Department of Genetics, Beth Israel Deaconess Medical Center 9:30 a.m. “Disorders of Axon Guidance-Eye Movements as a Paradigm” Elizabeth Engle, M.D., Professor of Neurology, Harvard Medical School; Department of Neurology, Children’s Hospital Boston 10:00 a.m. Coffee Break 10:30 a.m. Sir William Osler Young Investigator Award “Novel Approaches to Vaccine Development” Dan Hung Barouch, M.D., Associate Professor of Medicine, Harvard Medical School; Chief, Division of Vaccine Research, Beth Israel Deaconess Medical Center 11:00 a.m. “Pathways Regulating Blood Stem Cell Self Renewal” Leonard Ira Zon, M.D., Grousbeck Professor of Pediatrics, Harvard Medical School; Director, Stem Cell Research Program, Children’s Hospital Boston 11:30 a.m. “Functionalizing the Cancer Genome” Lynda Chin, M.D., Professor of Dermatology, Harvard Medical School; Scientific Director, Belfer Institute for Applied Cancer Science, Dana-Farber Cancer Center 12:00 p.m. Luncheon Speaker: “Harvard Medical School – Then and Now”, Jeffrey S. Flier, M.D., Dean of the Faculty of Medicine, Harvard Medical School 1:15 p.m. Visit to Countway Library Historical Archives 2:00 p.m. “Polycystic Kidney Disease – 3 mini stories” Jing Zhou, M.D., Ph.D., Associate Professor of Medicine, Harvard Medical School; Department of Medicine, Brigham and Women’s Hospital 2:30 p.m. “Targeting P13K for Cancer Treatment” Lewis C. Chantley, Ph.D., William Bosworth Castle Professor of Medicine, Harvard Medical School; Chief, Division of Signal Transduction, Beth Israel Deaconess Medical Center 3:00 p.m. Coffee Break 3:30 p.m. “Novel Mechanisms that Link Obesity and Diabetes Risk” Barbara Kahn, M.D., George Richards Minot Professor of Medicine, Harvard Medical School, Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center 4:00p.m. “Quality Improvement: Raising the Bar” Mark L. Zeidel, M.D., Herrman Ludwig Blumgart Professor of Medicine, Harvard Medical School; Chair, Department of Medicine, Beth Israel Deaconess Medical Center ❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊ 4:30 p.m. Business Meeting Harvard Medical School Benjamin Waterhouse Room, Gordon Hall 25 Shattuck Street Boston, MA 02115 ❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊ 6:30 p.m. Cocktail Reception The Harvard Club, 374 Commonwealth Ave., Boston, MA 02215 (617) 536-1260 7:00 p.m. Dinner (Black Tie) The Harvard Club 8:00 p.m. After Dinner Speaker: “Health Care Reform” Stuart Altman, Ph.D., Sol C. Chaikin Professor of National Health Policy, Brandeis University, Chair, Health Industry Forum; Chair, Council on the Economic Impact of Health System Change 9:00 p.m. Conclusion ❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊ Agenda for 201st MEETING OF THE INTERURBAN CLINICAL CLUB ADVANCES IN MEDICAL RESEARCH: A CELEBRATION OF OSLER YALE SCHOOL OF MEDICINE COHEN AUDITORIUM, HARRIS BUILDING YALE CHILD STUDY CENTER 230 SOUTH FRONTAGE ROAD NEW HAVEN, CT 06520 Friday, March 26, 2010 201ST Meeting of the Interurban Clinical Club (1905-2010) ADVANCES IN MEDICAL RESEARCH ❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊ 8:00 a.m. Continental Breakfast- Yale School of Medicine Jane Ellen Hope Building, First Floor 8:15 a.m. Opening of Meeting and Welcoming Remarks, Cohen Auditorium, Harris Building; John Wysolmerski, M.D., New Haven ICC Councilor, Professor, Section of Endocrinology & Metabolism, Yale University School of Medicine 8:30 a.m. “New Treatments forType 1 Diabetes” Kevan Herold, M.D., Professor of Immunobiology, Professor of Internal Medicine/Endocrinology, Yale University School of Medicine 9:00 a.m. “Understanding Autoimmune Disease; from Genotype to Phenotype” David Hafler, M.D., Professor and Gilbert H Glasser Chair of Neurology, Yale University School of Medicine 9:30 a.m. “Stem cells, inflammation and tumor immunity: From bedside to the bench and back” Madhav Dhodapkar, M.D., Arthur and Isabel Bunker Professor of Medicine, Chief, Section of Hematology, Department of Internal Medicine, Director of Hematologic Malignancies, Yale Cancer Center 10:00 a.m. Coffee Break 10:30 a.m. Sir William Osler Young Investigator Award “Human IL-23/Th17 pathway functions” Clara Abraham, M.D., Assistant Professor of Internal Medicine, Section of Digestive Diseases, Yale University School of Medicine 11:00 a.m. “MicroRNA’a and cancer” Frank Slack, Ph.D., Professor of Molecular, Cellular & Developmental Biology Yale University 11:30 a.m. “Personalized Therapy of Lung Cancer 2010” Thomas Lynch, M.D., Director of Yale Cancer Center and Physician-in-Chief of Smilow Cancer Hospital at Yale-New Haven 12:00 p.m. Lunch 12:15 p.m. Luncheon Speaker: “Undergraduate science curriculum reform and medical school admissions”, Robert Alpern, M.D., Dean, Yale School of Medicine, Professor of Internal Medicine Section of Nephrology 1:15 p.m. Preview of Cushing Archive with Dennis Spencer, M.D., Professor of Neurosurgery 2:00 p.m. “VEGF signaling and arterial morphogenesis” Michael Simons, M.D., Chief, Section of Cardiovascular Medicine, Professor of Medicine, Yale University School of Medicine 2:30 p.m. “Insulin-induced Hypoglycemia; The Brain Diabetes Connection” Robert Sherwin, M.D., C.N.H., Long Professor of Medicine, Section Chief, Section of Endocrinology & Metabolism, Yale University School of Medicine 3:00 p.m. Coffee Break 3:30 p.m. “Immunology of Asthma” Jack Elias, M.D. Chairman, Department of Internal Medicine, Waldemar Von Zedtwitz Professor of Medicine Chief, Beeson Medical Service YNHH, Yale University School of Medicine 4:00p.m. “CFTR in the Immune Response” Marie Egan, M.D., FAAP, Associate Professor of Pediatrics and Cellular and Molecular Physiology, Yale University School of Medicine ❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊ 4:30 p.m. Business Meeting Cohen Auditorium, Harris Building Yale Child Study Center 230 South Frontage Road New Haven, CT 06520 ❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊ 6:30 p.m. Cocktail Reception Quinnipiack Club, 221 Church Street, New Haven, CT 06510-1801 (203) 562-3147 7:00 p.m. Dinner (Black Tie) Quinnipiack Club 8:00 p.m. After Dinner Performance Yale Opera Program 9:00 p.m. Conclusion ❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊ Agenda for 200th MEETING OF THE INTERURBAN CLINICAL CLUB ADVANCES IN MEDICAL RESEARCH: A CELEBRATION OF OSLER JOHNS HOPKINS UNIVERSITY Cancer Research Building 2, Conference 111 1550 Orleans Street Baltimore, MD 21231 Friday, November 6, 2009 200th Meeting of the Interurban Clinical Club (1905-2009) Organizing Committee Honorary Chairperson Eve Osler Hampson Boston: Frank Austen, Ed Benz, Frank Bunn, Jeff Drazen, Kurt Isselbacher, John Potts, Tom Stossel, Megan Sykes*, Mark Zeidel New Haven: Jeffrey Bender, Arthur Broadus, Lloyd Cantley, Thomas Duffy, Jack Elias, Bernie Forget, John Forrest, Steve Malawista, John Wysolmerski* New York: Craig Basson*, Leonard Chess, Edward Fisher, Rochelle Hirschhorn, Richard Kitsis, Paul Marks, Aaron Marcus, David Shafritz, Babette Weksler Philadelphia: Barry Blumberg, Robert Coleman, Wafik El-Deiry*, Stephen Emerson, Jon Epstein, William Kelley, Richard Shannon*, Koneti Rao, Scott Waldman Baltimore: Mark Donowitz, Diane Griffin, Tom Hendrix, Richard Johns, Gerald Lazarus, Guy McKhann, Antony Rosen*, Richard Ross, Cynthia Sears, Mike Weisfeldt *Current ICC Officer or Councilor ADVANCES IN MEDICAL RESEARCH: A CELEBRATION OF OSLER ❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊ 7:30 a.m. Continental Breakfast- Johns Hopkins University (CRB 2, Conference 111) 8:00 a.m. Opening of Meeting and Welcoming Remarks (CRB 2, Conference 111) Richard P. Shannon, M.D., ICC President, Frank Wister Thomas Professor of Medicine, Chair, Department of Medicine, University of Pennsylvania School of Medicine Antony Rosen, M.D., Baltimore ICC Councilor, Professor and Director, Division of Rheumatology, Department of Medicine, Johns Hopkins University 8:10 a.m. “Welcoming Remarks from the Osler Family” Eve Osler Hampson, Great Grand Niece of Sir William Osler, Ottawa, Canada and Honorary Chairperson, 200th Interurban Clinical Club Meeting 8:25 a.m. “Welcome to Johns Hopkins and Baltimore” Edward D. Miller, M.D., Frances Watt Baker and Lenox D. Baker Jr. Dean of the School of Medicine, Chief Executive Officer, Johns Hopkins Medicine Morning Scientific Session (I): Chair, Cynthia L. Sears, M.D. Professor of Medicine and Oncology, Johns Hopkins University 8:30 a.m. “The Cancer Genome and Its Implications for Patients” Bert Vogelstein, M.D., Director, Ludwig Center at Johns Hopkins, Investigator, Howard Hughes Medical Institute 9:00 a.m. “The Human Microbiota in Health and Disease” Claire Fraser-Liggett, Ph.D., Professor of Medicine, Microbiology and Immunology, Director, Institute for Genome Sciences, University of Maryland School of Medicine 9:30 a.m. “Mechanistic analysis of Wilson's disease reveals new metabolic connections in the liver”, Svetlana Lutsenko, Ph.D., Visiting Professor of Physiology, Johns Hopkins University School of Medicine 10:00 a.m. Coffee Break Morning Scientific Session (II): Chair, Wafik S. El-Deiry, M.D., Ph.D., ICC Secretary/Treasurer and Philadelphia Councilor, American Cancer Society Professor, Professor of Medicine (Hematology/Oncology), Genetics, and Pharmacology, University of Pennsylvania School of Medicine 10:30 a.m. Sir William Osler Young Investigator Award “Reversing T cell inhibition in chronic viral infection: from bench to bedside...and back”, Andrea Cox, M.D., Ph.D., Associate Professor of Medicine and Oncology, Johns Hopkins University 11:00 a.m. “Thromboregulation: Blood and Vascular Cell Control of Platelet Reactivity in Hemostasis and Thrombosis”, Aaron Marcus, M.D., Chief, Hematology/Oncology Section, Medical Service, VA NY Harbor HS 11:30 a.m. “Reflections on Academic Leadership” William N. Kelley, M.D., Professor of Medicine, University of Pennsylvania School of Medicine 12:00 p.m. Lunch 12:15 p.m. Introduction: Cynthia L. Sears, M.D., Professor of Medicine and Oncology, Johns Hopkins University Luncheon Speaker: “Unlikely Allies: Sir William Osler, Mary Elizabeth Garrett and the Transformation of American Medicine” Kathleen Waters Sander, Ph.D., Adjunct Professor of History at the University of Maryland University College 1:15 p.m. Option of 2 activities: Tour of the Johns Hopkins’ Dome Charles Wiener, M.D., Professor of Medicine and Physiology, Vice-Chair of Education, Director, Osler Medical Housestaff Program, Johns Hopkins University School of Medicine Video presentation – William Osler & the teaching of microscopy at McGill Introduction by Eve Osler Hampson Afternoon Scientific Session: Chair, Mark Donowitz, M.D., LeBoff Professor for Research in Digestive Diseases, Director, Johns Hopkins Center for Epithelial Disorders, President, American Gastroenterological Association (2006-2007) 2:00 p.m. “Cognitive and Neurological Outcomes after Cardiac Surgery” Guy McKhann, M.D., Professor of Neurology and Neuroscience, Department of Neurology, The Center for Mind-Body Research, Johns Hopkins University 2:30 p.m. “LTE4, the overlooked cysteinyl leukotriene in inflammation” Frank Austen, M.D., Astra Zeneca Professor of Respiratory and Inflammatory Diseases, Department of Medicine, Harvard Medical School and Brigham and Women's Hospital 3:00 p.m. Break 3:30 p.m. “Osler’s Legacy in the Interurban Clinical Club” Thomas Duffy, M.D., Professor of Medicine/Hematology and Director, Program for Humanities in Medicine, Yale University School of Medicine 4:00 p.m. “Mechanisms of Hypoglycemia Associated Autonomic Failure” Stephen Davis, M.D., Incoming Professor, Physician-in-Chief and Theodore Woodward Chairman of Medicine, University of Maryland School of Medicine ❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊ 4:30 p.m. Business Meeting Johns Hopkins University, CRB 2, Conference 111, 1550 Orleans Street, Baltimore, MD 21231 ❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊ 6:30 p.m. Cocktail Reception Engineers Club, 11 West Mount Vernon Place, Baltimore, MD 21201 7:00 p.m. Dinner (Black Tie) Engineers Club, 11 West Mount Vernon Place, Baltimore, MD 21201 8:00 p.m. After Dinner Speaker “Osler: Founding Father of American Clinical Medicine” Michael Bliss, Ph.D., University Professor Emeritus, University of Toronto 9:00 p.m. Conclusion of Friday Program SATURDAY, NOVEMBER 7, 2009 200th MEETING OF THE INTERURBAN CLINICAL CLUB ADVANCES IN MEDICAL RESEARCH: A CELEBRATION OF OSLER JOHNS HOPKINS UNIVERSITY HURD HALL, 600 NORTH WOLFE STREET BALTIMORE, MD 21287 ❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊ 8:15 a.m. Breakfast (Hurd Hall) 8:40 a.m. Opening of Grand Rounds and Welcoming Remarks Johns Hopkins Hospital, Hurd Hall Cynthia Sears, M.D., Professor of Medicine and Oncology, Johns Hopkins University 8:45 a.m. Grand Rounds Image of Osler Amy E. Dezern, M.D., Assistant Chief of Service, Janeway Firm, Department of Medicine, Johns Hopkins University Maintaining skeletal muscle mass: Lessons learned from Muscular Dystrophy and Hibernation Ronald Cohn, M.D., Assistant Professor, Pediatrics and Neurology, McKusick-Nathans Institute of Genetic Medicine, Director, Johns Hopkins Center for Hypotonia Androgens, Androgen Action, and Prostate Cancer: New Insights into an Old Idea William G. Nelson, M.D., Ph.D., Marion I Knott Professor and Director, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University 9:45 a.m. Move to the Tilghman Auditorium in Turner Concourse Coffee Break Scientific session: Tilghman Auditorium, Tuner concourse Chair: Richard J. Johns, M.D., Distinguished Service Professor of Biomedical Engineering, Johns Hopkins University 10:15 a.m. "Atovaquone for malaria prophylaxis: A Stitch in time" Theresa A. Shapiro, M.D., Ph.D., Professor of Medicine, Director, Division of Clinical Pharmacology, Johns Hopkins University School of Medicine 10:45 a.m. "How HIV informed Medicine" John Bartlett, M.D., Stanhope Bayne-Jones Professor of Medicine (Infectious Diseases), Professor of Epidemiology, Johns Hopkins University School of Medicine 11:15 a.m. Wrap-up John N. Forrest, Jr., M.D., Professor of Medicine, Director, Office of Student Research, Yale University School of Medicine, Director, Mount Desert Island Biological Laboratory ❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊ AGENDA FOR 199th Meeting of the Interurban Clinical Club - Sir William Osler, Founder, 1905 ADVANCES IN MEDICAL RESEARCH THE COLLEGE OF PHYSICIANS OF PHILADELPHIA THOMSON HALL, 19 SOUTH 22nd STREET PHILADELPHIA, PA 19103 (215) 563-3103 FRIDAY, APRIL 3, 2009 199th Meeting of the Interurban Clinical Club (1905-2009) ❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊ 8:00 a.m. Continental Breakfast – The College of Physicians of Philadelphia (Thomson Hall) 8:20 a.m. Opening of Meeting and Welcoming Remarks The College of Physicians of Philadelphia; Thomson Hall Wafik S. El-Deiry, M.D., Ph.D., Philadelphia ICC Councilor, American Cancer Society Research Professor, Professor of Medicine, Genetics, and Pharmacology, Co-Director, Radiation Biology and Imaging Program, Abramson Cancer Center, University of Pennsylvania School of Medicine 8:30 a.m. “Wnt Signaling, Chromatin Structure, and Poised Transcription in Early Development” Peter S. Klein, M.D., Ph.D., Associate Professor, Departments of Medicine, and Cell and Developmental Biology, University of Pennsylvania School of Medicine 9:00 a.m. “Sleepless flies: Probing the genetics of sleep” Amita Seghal, Ph.D., Professor of Neuroscience, Investigator, Howard Hughes Medical Institute, University of Pennsylvania School of Medicine 9:30 a.m. “Stem Cells and Immunity in the 21st Century - The Quest for Vaccines against Stealthy Pathogens” Steven L. Reiner, M.D., Professor, Department of Medicine, Division of Infectious Diseases and Abramson Family Cancer Research Institute, Chair, Immunology Graduate Group, University of Pennsylvania School of Medicine 10:00 a.m. "Challenges in Spanning the Biology-Medicine Chasm-Lessons from Ovarian Cancer" Michael V. Seiden, M.D., Ph.D., President and CEO, Fox Chase Cancer Center 10:30 a.m. Coffee Break 11:00 “Developmental Biology Rounds: Molecular control of pancreatic development and cancer” Ben stanger, M.D., Ph.D., Assistant Professor of Medicine, Division of Gastroenterology, Assistant Investigator, Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine 11:30 a.m. Sir William Osler Young Investigator Award “Soluble and mechanical factors in liver fibrosis” Rebecca Wells, M.D., Assistant Professor, Departments of Medicine (Gastroenterology) and Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine 12:15 p.m. Luncheon Speaker: “Lessons Learned from the OTCD Trial” James M. Wilson, M.D., Ph.D., John Herr Musser Professor of Research Medicine, Professor, Department of Pathology and Laboratory Medicine, Head, Gene Therapy Program, University of Pennsylvania School of Medicine 1:15 p.m. Tour of The College of Physicians of Philadelphia Mütter Museum 2:00 p.m. “The imaging phenotype as a tool for disease characterization” Mitchell Schnall, M.D., Ph.D., Matthew J. Wilson Professor of Radiology and Vice Chair for Research, Department of Radiology, University of Pennsylvania School of Medicine 2:30 p.m. “An Aye for Gene Therapy: Preliminary Results from a Phase 1 Clinical Trial for Congenital Blindness” Jean Bennett, M.D., Ph.D., F.M. Kirby Professor, Ophthalmology, Cell and Developmental Biology, Vice Chair for Research in Ophthalmology, Senior Investigator, F.M. Kirby Center for Molecular Ophthalmology, University of Pennsylvania School of Medicine 3:00 p.m. "Caveolins in Breast Cancer Pathogenesis and Prevention: Role of the Tumor Micro-Environment" Michael P. Lisanti, M.D., Ph.D., Director, Stem Cell Biology and Regenerative Medicine Center, Director, Basic and Translational Science, Department of Medical Oncology, Landenberger Endowed Professor in Breast Cancer Research, Professor of Cancer Biology, Medical Oncology, and Biochemistry, Kimmel Cancer Center, Thomas Jefferson University 3:30 p.m. “Pediatric oncology at the crossroads: Meeting the challenge of stagnating cure rates with genomic medicine” John Maris, M.D., Chief, Division of Oncology, Associate Professor of Pediatrics, Director, Center for Childhood Cancer Research, Children’s Hospital of Philadelphia 4:00 p.m. “Hair follicle stem cells and skin regeneration” George Cotsarelis, M.D., Albert M. Kligman Associate Professor of Dermatology, Director, Program on Epithelial Regeneration and Stem Cells, University of Pennsylvania Institute for Regenerative Medicine, Director, University of Pennsylvania Hair and Scalp Clinic, University of Pennsylvania School of Medicine and Hospital of the University of Pennsylvania ❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊ 4:30 p.m. Business Meeting The College of Physicians of Philadelphia 19 S. 22nd Street Philadelphia, PA 19103 ❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊ 6:30 p.m. Cocktail Reception Union League 140 S. Broad Street Philadelphia, PA 19102 (215) 405-9578 7:00 p.m. Dinner (Black Tie) Union league 140 S. Broad Street Philadelphia, PA 19102 (215) 405-9578 8:00 p.m. After Dinner Speaker “Progress & Promise in the Fight Against Cancer” Margaret Foti, Ph.D., M.D. (h.c.), Chief Executive Officer, American Association for Cancer Research 9:00 p.m. Conclusion ❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊ AGENDA FOR 198th Meeting of the Interurban Clinical Club - Sir William Osler, Founder, 1905 ADVANCES IN MEDICAL RESEARCH Weill Medical College of Cornell University Starr 460 510 E. 70th Street New York, NY 10021 Friday, November 14, 2008 198th Meeting of the Interurban Clinical Club (1905-2008) ❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊ Morning Sessions will be in the Starr 460 Conference Room 8:30 a.m. Continental Breakfast 8:50 a.m. Opening of Meeting and Welcoming Remarks Craig T. Basson, M.D., Ph.D., Councilor, Gladys and Roland Harriman Professor of Medicine, Pediatrics, Cell & Developmental Biology, Director, Center for Molecular Cardiology, Weill Cornell Medical College 9:00 a.m. "Genome Wide Association Study for Cardiovascular Risk Factors on the Pacific Island of Kosrae" Jan Breslow, M.D., Professor, Head Laboratory of Biochemical Genetics and Metabolism, Rockefeller University; Senior Physician, Rockefeller Hospital 9:30 a.m. "Regulating Lymph Node Vascular Growth" Theresa T. Lu, M.D., Ph.D., Assistant Professor of Microbiology and Immunology, Weill Cornell Medical College; Assistant Member, Autoimmunity and Inflammation Program and Pediatric Rheumatology, Hospital for Special Surgery 10:00 a.m. "Genetic Reprogramming of T cells and B cells to Generate Potent HIV-Specific Immunity" Harris Goldstein, M.D., Professor of Pediatrics and Microbiology & Immunology, Director of Einstein/MMC Center for AIDS Research; Assistant Dean for Scientific Resources, Albert Einstein College of Medicine 10:30 a.m. Coffee Break 11:15 a.m. "Restoration of p53 Function for Induction of Apoptosis in Mutant p53 Cancer Cells by a p53 Custom Peptide: Design, Mechanisms, and In Vivo Efficacy" Robert L. Fine, M.D., Irving Associate Professor of Medicine, Director of Experimental Therapeutics, College of Physicians and Surgeons, Columbia University 11:45 a.m. "Preparing the “Soil” for the Metastatic Niche" David Lyden, M.D., Ph.D., Stavros S. Niarchos Associate Professor of Pediatrics and of Cell and Developmental Biology, Weill Cornell Medical College 12:15 p.m. Lunch 12:35 p.m. Luncheon Speaker: "Training Physician-Scientists for the 21st Century: Challenges and Opportunities" Olaf S. Andersen, M.D., Professor of Physiology and Biophysics, Thomas H. Meikle, Jr. Professor of Medical Education, Weill Cornell Medical College; Director, Weill Cornell/Rockefeller/Sloan-Kettering MD-PhD Program 1:25 p.m. Tour of the Weill Medical College of Cornell University Archives James L. Gehrlich, Archivist, Weill Cornell Medical College Afternoon Sessions will be in the Starr 460 Conference Room 1:55 p.m. "Evolutionary Dynamics of Cancer Stem Cells" Franziska Michor, Ph.D., Assistant Member, Computational Biology Program, Memorial Sloan Kettering Cancer Center 2:25 p.m. "Targeting Calcium Cycling in Heart Failure" Roger J. Hajjar, M.D., Arthur & Janet C. Ross Professor of Medicine, Director, Cardiovascular Research Center, Mt. Sinai School of Medicine 2:55 p.m. "Disorders of Sex Development: New Lingo, New Genes, New Mechanisms" Harry Ostrer, M.D., Professor of Pediatrics, Pathology and Medicine, Director, Human Genetics Program, New York University Langone Medical Center 3:25 p.m. Sir William Osler Young Investigator Award "Delayed Enhancement MRI for Left Atrial Appendage Thrombus Tissue Characterization" Jonathan W. Weinsaft, M.D., Michael J. Wolk Clinical Scholar, Assistant Professor of Medicine, Director, Cardiac MRI Program, Weill Cornell Medical College ❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊ 4:00 p.m. Business Meeting ❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊ 6:30 p.m. Cocktail Reception, Ristorante Primavera, 82nd St. & 1st Ave. 7:00 p.m. Dinner (Black Tie), Ristorante Primavera, 82nd St. & 1st Ave. 8:00 p.m. After Dinner Speaker: "Public versus Private Financing in Health Care: General Principles for Rich and Poor Countries" Jeffrey D. Sachs, Ph.D., Quetelet Professor of Sustainable Development, The Earth Institute, Columbia University, Special Advisor to the UN Secretary General Ban Ki-moon ❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊ AGENDA FOR 197th Meeting of the Interurban Clinical Club - Sir William Osler, Founder, 1905 ADVANCES IN MEDICAL RESEARCH Massachusetts General Hospital O’Keefe Auditorium 55 Fruit Street Boston, MA 02114 Friday, April 4, 2008 197th Meeting of the Interurban Clinical Club (1905-2008) ❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊ 8:15 a.m. Walk from Holiday Inn Select to Massachusetts General Hospital 8:30 a.m. Continental Breakfast Morning Session – O’Keefe Auditorium, Massachusetts General Hospital 8:50 a.m. Opening of Meeting and Welcoming Remarks, Megan Sykes, M.D., ICC Boston Councilor, Professor of Surgery and Medicine (Immunology), Harvard Medical School, Massachusetts General Hospital 9:00 a.m. "Not miR-ly small RNAs: Big potential for microRNAs in therapy" Carl D. Novina, M.D., Ph.D., Assistant Professor of Pathology, Harvard Medical School, Dana Farber Cancer Institute 9:30 a.m. "Learned Regulation of Brain Functions as a Potential Therapy" John D.E. Gabrieli, Ph.D., Grover Hermann Professor of Health and Technology and Cognitive Neuroscience, Massachusetts Institute of Technology 10:00 a.m. "Nanotechnology Advances to Enable Molecular Medicine" Ralph Weissleder, M.D., Ph.D., Professor of Radiology, Harvard Medical School, Massachusetts General Hospital 10:30 a.m. Coffee Break 11:15 a.m. "The immunological functions of the (not so) neonatal receptor for IgG, FcRn" Richard Blumberg, M.D., Professor of Medicine, Harvard Medical School, Brigham and Women’s Hospital 11:45 a.m. Sir William Osler Young Investigator Award "Genetic and Epigenetic Programs in Leukemia Stem Cells" Scott Armstrong, M.D., Ph.D., Assistant Professor of Pediatrics, Harvard Medical School, Dana Farber Cancer Institute 12:15 p.m. Lunch at O’Keefe Auditorium, Massachusetts General Hospital 12:45 p.m. Luncheon Speaker: "A Century of Disaster Response by Academic Medical Centers: Changing Priorities and Challenges" Susan Briggs, M.D., Associate Professor of Surgery, Harvard Medical School, Massachusetts General Hospital 1:30pm Tour of Massachusetts General Hospital Ether Dome Afternoon Session – O’Keefe Auditorium, Massachusetts General Hospital 2:30 p.m. "Regulating the T cell Regulators" David Hafler, M.D., Professor of Neurology (Neuroscience), Harvard Medical School, Brigham and Women’s Hospital 3:00 p.m. "Transplantation Tolerance: Can it overcome the limitations of this field?" David H. Sachs, M.D., Professor of Surgery (Immunology), Harvard Medical School, Massachusetts General Hospital 3:30 p.m. "Turning adult cells into embryonic stem cells" Konrad Hochedlinger, Ph.D. Assistant Professor of Medicine, Harvard Medical School, Massachusetts General Hospital ❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊ 4:00 p.m. Business meeting: O’Keefe Auditorium, Massachusetts General Hospital ❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊ 6:30 p.m. Cocktail Reception: Harvard Faculty Club, Cambridge, MA 7:00 p.m. Dinner (black-tie): Harvard Faculty Club, Cambridge, MA 8:00 p.m. "The Many Histories of Mind Body Medicine -- and Why They Matter Today" After Dinner Speaker: Anne Harrington, Ph.D., Professor of the History of Science, Harvard University 9:00 p.m. Conclusion ❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊❊ Web Site: Wafik S. El-Deiry, ICC Secretary/Treasurer webmaster, 2005- Email: wafik.eldeiry@gmail.com OFFICERS OF THE INTERURBAN CLUB ABOUT THE NORTHERN CITIES MEETING DATES ABOUT WILLIAM OSLER THE SIR WILLIAM OSLER YOUNG INVESTIGATOR AWARD